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Meningococcal meningitis Vaccination


Meningococcal meningitis is an acute bacterial disease that can cause systemic infection. There are 13 different serogroups of meningitis of which groups B and C are most common in the UK. Serogroup A and the less common W135 can cause serious epidemics which occur predominantly in the African meningitis belt from Senegal in the west to Ethiopia in the east. These serotypes have also been responsible for outbreaks in Saudi Arabia during the Hajj pilgrimages and in the city of Moscow in Russia in the past.

The disease is transmitted by sneezing, coughing or direct contact with respiratory secretions. The bacteria are found in the nasal passages of healthy individuals. Around 25% of adolescents and 5-11% of adults carry the bacteria.


Individuals should consider being vaccinated if they are travelling to a country where meningococcal meningitis is present and where their stay maybe prolonged or they are involved in activities which may increase the risk of exposure to the disease, for example, working in a healthcare setting and living closely with the local population.

Summary

Age of Use

2+ months

Doses Required

1-2

Schedule

N/A

Time before Travel

10 days

Booster Required

Enquire with Travel Pharmacist

Cost

from £40

When is quadrivalent meningitis vaccination indicated for travellers?

Vaccination with the quadrivalent vaccine (Menveo® or Nimenrix®) is recommended for the following people travelling to areas of high-risk of group A meningococcal meningitis (especially the African meningitis belt):

  • People staying for extended time periods, such as 1 month or more.
  • People engaging in high-risk holidays or work, such as backpacking, healthcare workers, or those living in rural communities.
  • People attending the Hajj (Mecca) and Umrah pilgrimages in Saudi Arabia.
  • Seasonal working in the Hajj area.
  • Children or adults with asplenia or splenic dysfunction if travelling to a country with increased risk of serogroups A, W135 and Y disease.

Saudi Arabia now requires proof of vaccination with an A, C, W135 and Y conjugate vaccine (Menveo® or Nimenrix®) for visitors arriving for the Hajj and Umrah pilgrimages, or for seasonal working in the Hajj areas.

Meningococcal C conjugate vaccine is part of the childhood immunization programme. This vaccine protects against group C disease only. Travellers should be immunised with the quadrivalent polysaccharide vaccine (Menveo® or Nimenrix®), even if they have previously received the Meningococcal conjugate vaccine.

When is quadrivalent meningitis vaccination contraindicated?

Do not give meningitis vaccine if the person:

  • Has a current severe febrile illness.
  • Has had a confirmed anaphylactic reaction to a previous dose of meningitis vaccine.
  • A confirmed anaphylactic reaction to a vaccine containing diphtheria toxoid, the CRM 197 carrier protein, or tetanus toxoid.

What are the adverse effects of quadrivalent meningitis vaccine?

Confirmed anaphylaxis after immunization is extremely rare, with anaphylactoid reactions reported for approximately 1 in every 500,000 doses.

Menveo®
Commonly reported reactions include injection site reactions (such as pain, erythema, induration, and pruritus), headache, nausea, rash, and malaise.

Nimenrix®
Commonly reported reactions include injection site reactions (such as pain, erythema, and swelling), headache, nausea, irritability, drowsiness and loss of appetite. Nimenrix® is a black triangle drug and as such it is still under intensive post-marketing surveillance by the Medicines and Healthcare products Regulatory Agency (MHRA).
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Wed: 9:00am - 6:30pm

Thur: 9:00am - 6:30pm

Fri: 9:00am - 6:30pm

Sat: 9:00am - 1:00pm

Sun: Closed

Contact us
t: 01582 591 616
e: customerservice@birdsfootpharmacy.co.uk
Birdsfoot Lane Pharmacy
255 Birdsfoot Lane, Luton, Bedfordshire, LU3 2HX
Superintendent Pharmacist : Mr Rupesh Shah
GPhC Pharmacist Reg No. : 2048914
GPhC Premises Reg No. : 1028845
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